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Inhibition of SREBP increases gefitinib sensitivity in non-small cell lung cancer cells
The clinical success of EGFR inhibitors in patients with lung cancer is limited by the inevitable development of treatment resistance. Here, we show that inhibition of SREBP increase gefitinib sensitivity in vitro and in vivo. Interference of SREBP1 binding partner MARVELD1 potentiate the therapeuti...
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| Yayımlandı: | Oncotarget |
|---|---|
| Asıl Yazarlar: | , , , , , , , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Impact Journals LLC
2016
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5239560/ https://ncbi.nlm.nih.gov/pubmed/27447558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.10721 |
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