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NNMT depletion contributes to liver cancer cell survival by enhancing autophagy under nutrient starvation
Nicotinamide N-methyl transferase (NNMT) transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide (NAM), producing 1-methylnicotinamide (1MNA). NNMT has been implicated in several cancer types and recently in metabolism, but its role in autophagy regulation has not yet been invest...
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| Publicado no: | Oncogenesis |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6085294/ https://ncbi.nlm.nih.gov/pubmed/30093610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41389-018-0064-4 |
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