Functional aspects of meningeal lymphatics in aging and Alzheimer’s disease

Aging is a major risk factor for many neurological pathologies and the mechanisms underlying brain aging remain elusive. Unlike other tissues, the central nervous system (CNS) parenchyma is devoid of lymphatic vasculature and removal of waste products is performed mainly through a paravascular route...

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Publicado en:Nature
Main Authors: Da Mesquita, Sandro, Louveau, Antoine, Vaccari, Andrea, Smirnov, Igor, Cornelison, R. Chase, Kingsmore, Kathryn M., Contarino, Christian, Onengut-Gumuscu, Suna, Farber, Emily, Raper, Daniel, Viar, Kenneth E., Powell, Romie D., Baker, Wendy, Dabhi, Nisha, Bai, Robin, Cao, Rui, Hu, Song, Rich, Stephen S., Munson, Jennifer M., Lopes, M. Beatriz, Overall, Christopher C., Acton, Scott T., Kipnis, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6085146/
https://ncbi.nlm.nih.gov/pubmed/30046111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-018-0368-8
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