CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature

Neuroinflammatory diseases, such as multiple sclerosis, are characterized by invasion of the brain with autoreactive T cells. The mechanism of how T cells acquire their encephalitogenic phenotype and trigger disease remains, however, unclear. The existence of lymphatic vessels in the meninges indica...

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Udgivet i:Nat Neurosci
Main Authors: Louveau, Antoine, Herz, Jasmin, Alme, Maria Nordheim, Salvador, Andrea Francesca, Dong, Michael Q., Viar, Kenneth E., Herod, Grace, Knopp, James, Setliff, Joshua, Lupi, Alexander L., Mesquita, Sandro Da, Frost, Elizabeth L, Gaultier, Alban, Harris, Tajie H., Cao, Rui, Hu, Song, Lukens, John R., Smirnov, Igor, Overall, Christopher C., Oliver, Guillermo, Kipnis, Jonathan
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214619/
https://ncbi.nlm.nih.gov/pubmed/30224810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0227-9
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