CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature

Neuroinflammatory diseases, such as multiple sclerosis, are characterized by invasion of the brain with autoreactive T cells. The mechanism of how T cells acquire their encephalitogenic phenotype and trigger disease remains, however, unclear. The existence of lymphatic vessels in the meninges indica...

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Detalhes bibliográficos
Publicado no:Nat Neurosci
Main Authors: Louveau, Antoine, Herz, Jasmin, Alme, Maria Nordheim, Salvador, Andrea Francesca, Dong, Michael Q., Viar, Kenneth E., Herod, Grace, Knopp, James, Setliff, Joshua, Lupi, Alexander L., Mesquita, Sandro Da, Frost, Elizabeth L, Gaultier, Alban, Harris, Tajie H., Cao, Rui, Hu, Song, Lukens, John R., Smirnov, Igor, Overall, Christopher C., Oliver, Guillermo, Kipnis, Jonathan
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214619/
https://ncbi.nlm.nih.gov/pubmed/30224810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41593-018-0227-9
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