GenomeDISCO: a concordance score for chromosome conformation capture experiments using random walks on contact map graphs

MOTIVATION: The three-dimensional organization of chromatin plays a critical role in gene regulation and disease. High-throughput chromosome conformation capture experiments such as Hi-C are used to obtain genome-wide maps of three-dimensional chromatin contacts. However, robust estimation of data q...

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Библиографические подробности
Опубликовано в: :Bioinformatics
Главные авторы: Ursu, Oana, Boley, Nathan, Taranova, Maryna, Wang, Y X Rachel, Yardimci, Galip Gurkan, Stafford Noble, William, Kundaje, Anshul
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2018
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Original Papers
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084597/
https://ncbi.nlm.nih.gov/pubmed/29554289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/bty164
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