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Strategies for enhancing adoptive T-cell immunotherapy against solid tumors using engineered cytokine signaling and other modalities

INTRODUCTION: Cancer therapy has been transformed by the demonstration that tumor-specific T-cells can eliminate tumor cells in a clinical setting with minimal long-term toxicity. However significant success in the treatment of leukemia and lymphoma with T-cells using native receptors or redirected...

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Detalhes bibliográficos
Publicado no:Expert Opin Biol Ther
Main Authors: Shum, Thomas, Kruse, Robert L., Rooney, Cliona M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084433/
https://ncbi.nlm.nih.gov/pubmed/29727246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14712598.2018.1473368
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