Intron distribution difference for 276 ancient and 131 modern genes suggests the existence of ancient introns

Do introns delineate elements of protein tertiary structure? This issue is crucial to the debate about the role and origin of introns. We present an analysis of the full set of proteins with known three-dimensional structures that have homologs with intron positions recorded in GenBank. A computer p...

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Bibliographic Details
Main Authors: Fedorov, Alexei, Cao, Xiaohong, Saxonov, Serge, de Souza, Sandro J., Roy, Scott W., Gilbert, Walter
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC60844/
https://ncbi.nlm.nih.gov/pubmed/11687643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231491498
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