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Metabolic modeling of energy balances in Mycoplasma hyopneumoniae shows that pyruvate addition increases growth rate

Mycoplasma hyopneumoniae is cultured on large‐scale to produce antigen for inactivated whole‐cell vaccines against respiratory disease in pigs. However, the fastidious nutrient requirements of this minimal bacterium and the low growth rate make it challenging to reach sufficient biomass yield for an...

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Detalhes bibliográficos
Publicado no:Biotechnol Bioeng
Main Authors: Kamminga, Tjerko, Slagman, Simen‐Jan, Bijlsma, Jetta J. E., Martins dos Santos, Vitor A. P., Suarez‐Diez, Maria, Schaap, Peter J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084303/
https://ncbi.nlm.nih.gov/pubmed/28600895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bit.26347
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