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Succinct synthesis of saturated hydroxy fatty acids and in vitro evaluation of all hydroxylauric acids on FFA1, FFA4 and GPR84

Saturated hydroxy fatty acids make up a class of underexplored lipids with potentially interesting biological activities. We report a succinct and general synthetic route to saturated hydroxy fatty acids hydroxylated at position 6 or higher, and exemplify this with the synthesis of hydroxylauric aci...

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Vydáno v:Medchemcomm
Hlavní autoři: Kaspersen, Mads Holmgaard, Jenkins, Laura, Dunlop, Julia, Milligan, Graeme, Ulven, Trond
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6084075/
https://ncbi.nlm.nih.gov/pubmed/30108848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7md00130d
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