Possible Involvement of Mitochondrial Dysfunction and Oxidative Stress in a Cellular Model of NAFLD Progression Induced by Benzo[a]pyrene/Ethanol CoExposure

Exposure to xenobiotics could favor the transition of nonalcoholic fatty liver (NAFL) to nonalcoholic steatohepatitis in obese patients. Recently, we showed in different models of NAFL that benzo[a]pyrene (B[a]P) and ethanol coexposure induced a steatohepatitis-like state. One model was HepaRG cells...

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Dettagli Bibliografici
Pubblicato in:Oxid Med Cell Longev
Autori principali: Bucher, Simon, Le Guillou, Dounia, Allard, Julien, Pinon, Grégory, Begriche, Karima, Tête, Arnaud, Sergent, Odile, Lagadic-Gossmann, Dominique, Fromenty, Bernard
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2018
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083493/
https://ncbi.nlm.nih.gov/pubmed/30147834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/4396403
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