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Inverse agonism of retinoic acid receptors directs epiblast cells into the paraxial mesoderm lineage

We have investigated the differentiation of paraxial mesoderm from mouse embryonic stem cells utilizing a Tbx6-EYFP/Brachyury (T)-Ckerry dual reporter system. Differentiation from the mouse ESC state directly into mesoderm via Wnt pathway activation was low, but augmented by treatment with AGN193109...

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Bibliografiske detaljer
Udgivet i:Stem Cell Res
Main Authors: Russell, Ryan P., Fu, Yu, Liu, Yaling, Maye, Peter
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083448/
https://ncbi.nlm.nih.gov/pubmed/29807258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2018.05.016
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