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Inverse agonism of retinoic acid receptors directs epiblast cells into the paraxial mesoderm lineage
We have investigated the differentiation of paraxial mesoderm from mouse embryonic stem cells utilizing a Tbx6-EYFP/Brachyury (T)-Ckerry dual reporter system. Differentiation from the mouse ESC state directly into mesoderm via Wnt pathway activation was low, but augmented by treatment with AGN193109...
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| Veröffentlicht in: | Stem Cell Res |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6083448/ https://ncbi.nlm.nih.gov/pubmed/29807258 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.scr.2018.05.016 |
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