STF-083010, an inhibitor of XBP1 splicing, attenuates acute renal failure in rats by suppressing endoplasmic reticulum stress-induced apoptosis and inflammation

Endoplasmic reticulum (ER) stress is one of the driving forces of ischemia/reperfusion (IR)-induced acute renal failure (ARF). STF-083010, an inhibitor of the endonuclease activity of inositol-requiring enzyme-1 (IRE1), has the potential to block the initiation of a prolonged unfolded protein respon...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Exp Anim
Main Authors: Liu, Lei, Xu, Lu, Zhang, Shaoqing, Wang, Dong, Dong, Guoxia, Chen, Hanwen, Li, Xinjian, Shu, Chi, Wang, Rong
Formato: Artigo
Idioma:Inglês
Publicado em: Japanese Association for Laboratory Animal Science 2018
Assuntos:
Original
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6083033/
https://ncbi.nlm.nih.gov/pubmed/29695649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1538/expanim.17-0131
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados