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Transgenic mice produced by retroviral transduction of male germ-line stem cells

Male germ-line stem cells are the only cell type in postnatal mammals that have the capability to self-renew and to contribute genes to the next generation. Genetic modification of these cells would provide an opportunity to study the biology of their complex self-renewal and differentiation process...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Nagano, Makoto, Brinster, Clayton J., Orwig, Kyle E., Ryu, Buom-Yong, Avarbock, Mary R., Brinster, Ralph L.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2001
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC60829/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11606778/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.231473498
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