Transgenic mice produced by retroviral transduction of male germ-line stem cells

Male germ-line stem cells are the only cell type in postnatal mammals that have the capability to self-renew and to contribute genes to the next generation. Genetic modification of these cells would provide an opportunity to study the biology of their complex self-renewal and differentiation process...

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Bibliographic Details
Main Authors: Nagano, Makoto, Brinster, Clayton J., Orwig, Kyle E., Ryu, Buom-Yong, Avarbock, Mary R., Brinster, Ralph L.
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC60829/
https://ncbi.nlm.nih.gov/pubmed/11606778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.231473498
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