Molecular architecture of the multifunctional collagen lysyl hydroxylase and glycosyltransferase LH3

Lysyl hydroxylases catalyze hydroxylation of collagen lysines, and sustain essential roles in extracellular matrix (ECM) maturation and remodeling. Malfunctions in these enzymes cause severe connective tissue disorders. Human lysyl hydroxylase 3 (LH3/PLOD3) bears multiple enzymatic activities, as it...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Scietti, Luigi, Chiapparino, Antonella, De Giorgi, Francesca, Fumagalli, Marco, Khoriauli, Lela, Nergadze, Solomon, Basu, Shibom, Olieric, Vincent, Cucca, Lucia, Banushi, Blerida, Profumo, Antonella, Giulotto, Elena, Gissen, Paul, Forneris, Federico
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082870/
https://ncbi.nlm.nih.gov/pubmed/30089812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-05631-5
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