Peroxisome Proliferator-Activated Receptor gamma negatively regulates liver regeneration after partial hepatectomy via the HGF/c-Met/ERK1/2 pathways

Peroxisome Proliferator-Activated Receptor gamma (PPARγ) is a nuclear receptor demonstrated to play an important role in various biological processes. The aim of this study was to determine the effect of PPARγ on liver regeneration upon partial hepatectomy (PH) in mice. Mice were subjected to two-th...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Cheng, Zhangjun, Liu, Lei, Zhang, Xue-Jun, Lu, Miao, Wang, Yang, Assfalg, Volker, Laschinger, Melanie, von Figura, Guido, Sunami, Yoshiaki, Michalski, Christoph W., Kleeff, Jörg, Friess, Helmut, Hartmann, Daniel, Hüser, Norbert
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2018
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6082852/
https://ncbi.nlm.nih.gov/pubmed/30089804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-30426-5
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