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Exploring conformational states and helical packings in the P2X receptor transmembrane domain by molecular dynamics simulation
The P2X receptor is a trimeric transmembrane protein that acts as an ATP-gated ion channel. Its transmembrane domain (TMD) contains only six helices and three of them, the M2 helices, line the ion conduction pathway. Here, using molecular dynamics simulation, I identify four conformational states of...
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| Publicado no: | J Biol Phys |
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| Autor principal: | |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6082803/ https://ncbi.nlm.nih.gov/pubmed/29611030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10867-018-9493-8 |
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