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Formal [4+2] Cycloaddition of Imines with Alkoxyisocoumarins
A new preparation of δ-lactams is reported. In the presence of a Lewis acid promoter, alkoxyisocoumarins engage a range of N-aryl and N-alkyl imines to form δ-lactams with a pendent carboalkoxy substituent. A sulfonamide-thiourea catalyst enables the synthesis of these products in moderate to good e...
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| Publicado no: | Org Biomol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6082175/ https://ncbi.nlm.nih.gov/pubmed/29796555 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8ob01015c |
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