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Palladium-Catalyzed Asymmetric [3+2] Cycloaddition of Trimethylenemethane with Imines

The transition metal catalyzed trimethylenemethane [3+2] cycloaddition provides a direct route to functionalized heterocycles. Herein, we describe a catalytic, asymmetric protocol for the reaction between 3-acetoxy-2-trimethylsilylmethyl-1-propene and various imines. The corresponding pyrrolidines w...

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Autors principals: Trost, Barry M., Silverman, Steven M., Stambuli, James P.
Format: Artigo
Idioma:Inglês
Publicat: 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2532588/
https://ncbi.nlm.nih.gov/pubmed/17887679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja0753389
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