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Effect of buffer additives on solubilization and refolding of reteplase inclusion bodies
Reteplase is a non-glycosylated and recombinant form of tissue type plasminogen activator, which is produced in Escherichia coli. However, its overexpression usually leads to formation of inactive aggregates or inclusion bodies. In the present study, we report on the development of optimized process...
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| Publicado no: | Res Pharm Sci |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Medknow Publications & Media Pvt Ltd
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6082031/ https://ncbi.nlm.nih.gov/pubmed/30271443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/1735-5362.236834 |
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