Greater tau load and reduced cortical thickness in APOE ε4-negative Alzheimer’s disease: a cohort study

BACKGROUND: Alzheimer’s disease is characterized by aggregated β-amyloid and tau proteins, but the clinical presentations and patterns of brain atrophy vary substantially. A part of this heterogeneity may be linked to the risk allele APOE ε4. The spread of tau pathology is related to atrophy and cog...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Alzheimers Res Ther
Prif Awduron: Mattsson, Niklas, Ossenkoppele, Rik, Smith, Ruben, Strandberg, Olof, Ohlsson, Tomas, Jögi, Jonas, Palmqvist, Sebastian, Stomrud, Erik, Hansson, Oskar
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2018
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081879/
https://ncbi.nlm.nih.gov/pubmed/30086796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-018-0403-x
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg