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Greater tau load and reduced cortical thickness in APOE ε4-negative Alzheimer’s disease: a cohort study
BACKGROUND: Alzheimer’s disease is characterized by aggregated β-amyloid and tau proteins, but the clinical presentations and patterns of brain atrophy vary substantially. A part of this heterogeneity may be linked to the risk allele APOE ε4. The spread of tau pathology is related to atrophy and cog...
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| 出版年: | Alzheimers Res Ther |
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| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6081879/ https://ncbi.nlm.nih.gov/pubmed/30086796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-018-0403-x |
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