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Virtual memory cells make a major contribution to the response of aged influenza-naïve mice to influenza virus infection

BACKGROUND: A diverse repertoire of naïve T cells is thought to be essential for a robust response to new infections. However, a key aspect of aging of the T cell compartment is a decline in numbers and diversity of peripheral naïve T cells. We have hypothesized that the age-related decline in naïve...

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Pubblicato in:Immun Ageing
Autori principali: Lanzer, Kathleen G., Cookenham, Tres, Reiley, William W., Blackman, Marcia A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081820/
https://ncbi.nlm.nih.gov/pubmed/30093911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12979-018-0122-y
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