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Preclinical Optimization of Antibody-based Radiopharmaceuticals for Cancer Imaging and Radionuclide Therapy – Model, Vector, and Radionuclide Selection

Intact antibodies and their truncated counterparts (e.g. Fab, scFv fragments) are generally exquisitely specific and selective vectors, enabling recognition of individual cancer-associated molecular phenotypes against a complex and dynamic biomolecular background. Complementary alignment of these ad...

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Detalhes bibliográficos
Publicado no:J Labelled Comp Radiopharm
Main Authors: Carter, Lukas M., Poty, Sophie, Sharma, Sai Kiran, Lewis, Jason S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081268/
https://ncbi.nlm.nih.gov/pubmed/29412489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jlcr.3612
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