Polymorphisms of DNA repair genes are associated with colorectal cancer in patients with Lynch syndrome

BACKGROUND: DNA repair genes are crucial for maintaining genomic stability by preventing mutagenesis and carcinogenesis. The present retrospective cohort study aimed at investigating whether MLH1,APEX1,MUTYH,OGG1,NUDT1,XRCC5, XPA, and ERCC2 single nucleotide polymorphisms (SNPs) are associated with...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Genet Genomic Med
Auteurs principaux: Kamiza, Abram B., Hsieh, Ling‐Ling, Tang, Reiping, Chien, Huei‐Tzu, Lai, Chih‐Hsiung, Chiu, Li‐Ling, Lo, Tsai‐Ping, Hung, Kuan‐Yi, You, Jeng‐Fu, Wang, Wen‐Chang, Hsiung, Chao A., Yeh, Chih‐Ching
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2018
Sujets:
Original Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081223/
https://ncbi.nlm.nih.gov/pubmed/29664240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.402
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