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Polymorphisms of DNA repair genes are associated with colorectal cancer in patients with Lynch syndrome

BACKGROUND: DNA repair genes are crucial for maintaining genomic stability by preventing mutagenesis and carcinogenesis. The present retrospective cohort study aimed at investigating whether MLH1,APEX1,MUTYH,OGG1,NUDT1,XRCC5, XPA, and ERCC2 single nucleotide polymorphisms (SNPs) are associated with...

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Detalhes bibliográficos
Publicado no:Mol Genet Genomic Med
Main Authors: Kamiza, Abram B., Hsieh, Ling‐Ling, Tang, Reiping, Chien, Huei‐Tzu, Lai, Chih‐Hsiung, Chiu, Li‐Ling, Lo, Tsai‐Ping, Hung, Kuan‐Yi, You, Jeng‐Fu, Wang, Wen‐Chang, Hsiung, Chao A., Yeh, Chih‐Ching
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6081223/
https://ncbi.nlm.nih.gov/pubmed/29664240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mgg3.402
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