Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance

Growth cones navigate axonal projection in response to guidance cues. However, it is unclear how they can decide the migratory direction by transducing the local spatial cues into protrusive forces. Here we show that knockout mice of Shootin1 display abnormal projection of the forebrain commissural...

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Bibliografiske detaljer
Udgivet i:eLife
Main Authors: Baba, Kentarou, Yoshida, Wataru, Toriyama, Michinori, Shimada, Tadayuki, Manning, Colleen F, Saito, Michiko, Kohno, Kenji, Trimmer, James S, Watanabe, Rikiya, Inagaki, Naoyuki
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications, Ltd 2018
Fag:
Cell Biology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080949/
https://ncbi.nlm.nih.gov/pubmed/30082022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.34593
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