Gradient-reading and mechano-effector machinery for netrin-1-induced axon guidance

Growth cones navigate axonal projection in response to guidance cues. However, it is unclear how they can decide the migratory direction by transducing the local spatial cues into protrusive forces. Here we show that knockout mice of Shootin1 display abnormal projection of the forebrain commissural...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Baba, Kentarou, Yoshida, Wataru, Toriyama, Michinori, Shimada, Tadayuki, Manning, Colleen F, Saito, Michiko, Kohno, Kenji, Trimmer, James S, Watanabe, Rikiya, Inagaki, Naoyuki
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2018
Matèries:
Cell Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080949/
https://ncbi.nlm.nih.gov/pubmed/30082022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.34593
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