Ca(2+)–mitochondria axis drives cell division in hematopoietic stem cells

Most of the hematopoietic stem cells (HSCs) within the bone marrow (BM) show quiescent state with a low mitochondrial membrane potential (ΔΨ(m)). In contrast, upon stress hematopoiesis, HSCs actively start to divide. However, the underlying mechanism for the initiation of HSC division still remains...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Umemoto, Terumasa, Hashimoto, Michihiro, Matsumura, Takayoshi, Nakamura-Ishizu, Ayako, Suda, Toshio
Format: Artigo
Jezik:Inglês
Izdano: Rockefeller University Press 2018
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080917/
https://ncbi.nlm.nih.gov/pubmed/29946000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180421
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