IgA regulates the composition and metabolic function of gut microbiota by promoting symbiosis between bacteria

Immunoglobulin A (IgA) promotes health by regulating the composition and function of gut microbiota, but the molecular requirements for such homeostatic IgA function remain unknown. We found that a heavily glycosylated monoclonal IgA recognizing ovalbumin coats Bacteroides thetaiotaomicron (B. theta...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Nakajima, Akira, Vogelzang, Alexis, Maruya, Mikako, Miyajima, Michio, Murata, Megumi, Son, Aoi, Kuwahara, Tomomi, Tsuruyama, Tatsuaki, Yamada, Satoshi, Matsuura, Minoru, Nakase, Hiroshi, Peterson, Daniel A., Fagarasan, Sidonia, Suzuki, Keiichiro
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080902/
https://ncbi.nlm.nih.gov/pubmed/30042191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180427
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