BST-2 controls T cell proliferation and exhaustion by shaping the early distribution of a persistent viral infection

The interferon inducible protein, BST-2 (or, tetherin), plays an important role in the innate antiviral defense system by inhibiting the release of many enveloped viruses. Consequently, viruses have evolved strategies to counteract the anti-viral activity of this protein. While the mechanisms by whi...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Urata, Shuzo, Kenyon, Elizabeth, Nayak, Debasis, Cubitt, Beatrice, Kurosaki, Yohei, Yasuda, Jiro, de la Torre, Juan C., McGavern, Dorian B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2018
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080785/
https://ncbi.nlm.nih.gov/pubmed/30028868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007172
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