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Complexes of α6β4 integrin and vimentin act as signaling hubs to regulate epithelial cell migration

We find that clusters of β4 integrin, organized into distinct puncta, localize along vimentin filaments within lamellipodia at the cell edge of A549 cells, as assessed by interferometric photoactivated localization microscopy. Moreover, puncta and vimentin filaments exhibit a dynamic interplay in li...

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Sci
Hauptverfasser: Colburn, Zachary T., Jones, Jonathan C. R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080603/
https://ncbi.nlm.nih.gov/pubmed/29976561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.214593
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