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N-Glycosylation of integrin α5 acts as a switch for EGFR-mediated complex formation of integrin α5β1 to α6β4

N-Glycosylation of integrin α5β1 is involved in multiple cell behaviors. We previously reported that the N-glycosylations of the calf domain on integrin α5 (S3–5,10–14) are essential for its inhibitory effect on EGFR signaling in regulating cell proliferation. However, the importance of the individu...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Hang, Qinglei, Isaji, Tomoya, Hou, Sicong, Zhou, Ying, Fukuda, Tomohiko, Gu, Jianguo
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5027594/
https://ncbi.nlm.nih.gov/pubmed/27641064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep33507
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