A Key Regulator of Cell Adhesion: Identification and Characterization of Important N-Glycosylation Sites on Integrin α5 for Cell Migration

The N-glycosylation of integrin α5β1 is thought to control many fundamental aspects of cell behavior, including cell adhesion and migration. However, the mechanism of how N-glycans function remains largely obscure. Here, we used a loss-of-function approach. Wild-type (WT) integrin α5 and N-glycosyla...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Hang, Qinglei, Isaji, Tomoya, Hou, Sicong, Wang, Yuqin, Fukuda, Tomohiko, Gu, Jianguo
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5394273/
https://ncbi.nlm.nih.gov/pubmed/28167607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00558-16
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