A carregar...

The crystal structure of human protein farnesyltransferase reveals the basis for inhibition by CaaX tetrapeptides and their mimetics

Protein farnesyltransferase (FTase) catalyzes the attachment of a farnesyl lipid group to the cysteine residue located in the C-terminal tetrapeptide of many essential signal transduction proteins, including members of the Ras superfamily. Farnesylation is essential both for normal functioning of th...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Long, Stephen B., Hancock, Paula J., Kral, Astrid M., Hellinga, Homme W., Beese, Lorena S.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC60805/
https://ncbi.nlm.nih.gov/pubmed/11687658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.241407898
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!