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Sertoli Cells Engineered to Express Insulin to Lower Blood Glucose in Diabetic Mice
Long-term survival of allo- and xenotransplanted immune-privileged Sertoli cells (SCs) is well documented suggesting that SCs can be used to deliver foreign proteins for cell-based gene therapy. The aim of this study was to use a lentivirus carrying proinsulin cDNA to achieve stable expression and l...
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| Udgivet i: | DNA Cell Biol |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Mary Ann Liebert, Inc.
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6080125/ https://ncbi.nlm.nih.gov/pubmed/29927618 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dna.2017.3937 |
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