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Sequential Experimental Design for Optimal Structural Intervention in Gene Regulatory Networks Based on the Mean Objective Cost of Uncertainty

Scientists are attempting to use models of ever-increasing complexity, especially in medicine, where gene-based diseases such as cancer require better modeling of cell regulation. Complex models suffer from uncertainty and experiments are needed to reduce this uncertainty. Because experiments can be...

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Bibliografiske detaljer
Udgivet i:Cancer Inform
Main Authors: Imani, Mahdi, Dehghannasiri, Roozbeh, Braga-Neto, Ulisses M, Dougherty, Edward R
Format: Artigo
Sprog:Inglês
Udgivet: SAGE Publications 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6080085/
https://ncbi.nlm.nih.gov/pubmed/30093796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1176935118790247
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