Structural genomics of enzymes involved in sterol/isoprenoid biosynthesis

X-ray structures of two enzymes in the sterol/isoprenoid biosynthesis pathway have been determined in a structural genomics pilot study. Mevalonate-5-diphosphate decarboxylase (MDD) is a single-domain α/β protein that catalyzes the last of three sequential ATP-dependent reactions which convert meval...

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Main Authors: Bonanno, Jeffrey B., Edo, Carme, Eswar, Narayanan, Pieper, Ursula, Romanowski, Michael J., Ilyin, Valentin, Gerchman, Sue Ellen, Kycia, Helen, Studier, F. William, Sali, Andrej, Burley, Stephen K.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences 2001
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC60796/
https://ncbi.nlm.nih.gov/pubmed/11698677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.181466998
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