Polymer-Mediated Inhibition of Pro-invasive Nucleic Acid DAMPs and Microvesicles Limits Pancreatic Cancer Metastasis

Nucleic acid binding polymers (NABPs) have been extensively used as vehicles for DNA and RNA delivery. More recently, we discovered that a subset of these NABPs can also serve as anti-inflammatory agents by capturing pro-inflammatory extracellular nucleic acids and associated protein complexes that...

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Foilsithe in:Mol Ther
Main Authors: Naqvi, Ibtehaj, Gunaratne, Ruwan, McDade, Jessica E., Moreno, Angelo, Rempel, Rachel E., Rouse, Douglas C., Herrera, Silvia Gabriela, Pisetsky, David S., Lee, Jaewoo, White, Rebekah R., Sullenger, Bruce A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society of Gene & Cell Therapy 2018
Ábhair:
Original Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079560/
https://ncbi.nlm.nih.gov/pubmed/29550075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.02.018
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