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Nucleic acid-binding polymers as anti-inflammatory agents

Dead and dying cells release nucleic acids. These extracellular RNAs and DNAs can be taken up by inflammatory cells and activate multiple nucleic acid-sensing toll-like receptors (TLR3, 7, 8, and 9). The inappropriate activation of these TLRs can engender a variety of inflammatory and autoimmune dis...

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Bibliografski detalji
Glavni autori: Lee, Jaewoo, Sohn, Jang Wook, Zhang, Ying, Leong, Kam W., Pisetsky, David, Sullenger, Bruce A.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3161575/
https://ncbi.nlm.nih.gov/pubmed/21844380
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105777108
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