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Nucleic acid-binding polymers as anti-inflammatory agents
Dead and dying cells release nucleic acids. These extracellular RNAs and DNAs can be taken up by inflammatory cells and activate multiple nucleic acid-sensing toll-like receptors (TLR3, 7, 8, and 9). The inappropriate activation of these TLRs can engender a variety of inflammatory and autoimmune dis...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3161575/ https://ncbi.nlm.nih.gov/pubmed/21844380 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105777108 |
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