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Neonatal Systemic AAV-Mediated Gene Delivery of GDF11 Inhibits Skeletal Muscle Growth

Growth and differentiation factor 11 (GDF11; BMP11) is a circulating cytokine in the transforming growth factor beta (TGF-β) superfamily. Treatment with recombinant GDF11 (rGDF11) protein has previously been shown to reverse skeletal muscle dysfunction in aged mice. However, the actions of GDF11 in...

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Bibliografische gegevens
Gepubliceerd in:Mol Ther
Hoofdauteurs: Jin, Quan, Qiao, Chunping, Li, Jianbin, Li, Juan, Xiao, Xiao
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Gene & Cell Therapy 2018
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079557/
https://ncbi.nlm.nih.gov/pubmed/29503194
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.01.016
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