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Tigecycline as a dual inhibitor of retinoblastoma and angiogenesis via inducing mitochondrial dysfunctions and oxidative damage

Retinoblastoma is the most common intraocular malignancy in children with poor prognosis. The progression of retinoblastoma is dependent on a robust angiogenic response. Targeting both retinoblastoma cells and angiogenesis may therefore provide an alternative therapeutic strategy in retinoblastoma....

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xiong, Ying, Liu, Wei, Huang, Qian, Wang, Jierong, Wang, Yanjun, Li, Huijuan, Fu, Xuedong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6079108/
https://ncbi.nlm.nih.gov/pubmed/30082885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29938-x
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