Metabolism of ticagrelor in patients with acute coronary syndromes

Ticagrelor is a state-of-the-art antiplatelet agent used for the treatment of patients with acute coronary syndromes (ACS). Unlike remaining oral P2Y12 receptor inhibitors ticagrelor does not require metabolic activation to exert its antiplatelet action. Still, ticagrelor is extensively metabolized...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Adamski, Piotr, Buszko, Katarzyna, Sikora, Joanna, Niezgoda, Piotr, Barańska, Malwina, Ostrowska, Małgorzata, Paciorek, Przemysław, Navarese, Eliano P., Gorog, Diana A., Kubica, Jacek
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078957/
https://ncbi.nlm.nih.gov/pubmed/30082687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-29619-9
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