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Protective effects of reduced dynamin-related protein 1 against amyloid beta-induced mitochondrial dysfunction and synaptic damage in Alzheimer’s disease

The purpose of our study was to understand the protective effects of reduced expression of dynamin-related protein (Drp1) against amyloid beta (Aβ) induced mitochondrial and synaptic toxicities in Alzheimer’s disease (AD) progression and pathogenesis. Our recent molecular and biochemical studies rev...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Manczak, Maria, Kandimalla, Ramesh, Fry, David, Sesaki, Hiromi, Reddy, P. Hemachandra
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078633/
https://ncbi.nlm.nih.gov/pubmed/27677309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw330
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