Independent variability of microtubule perturbations associated with dystrophinopathy

Absence of the protein dystrophin causes Duchenne muscular dystrophy. Dystrophin directly binds to microtubules in vitro, and its absence in vivo correlates with disorganization of the subsarcolemmal microtubule lattice, increased detyrosination of α-tubulin, and altered redox signaling. We previous...

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Publicat a:Hum Mol Genet
Autors principals: Belanto, Joseph J., Olthoff, John T., Mader, Tara L., Chamberlain, Christopher M., Nelson, D’anna M., McCourt, Preston M., Talsness, Dana M., Gundersen, Gregg G., Lowe, Dawn A., Ervasti, James M.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078591/
https://ncbi.nlm.nih.gov/pubmed/28171583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw318
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