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Epistasis and destabilizing mutations shape gene expression variability in humans via distinct modes of action
Increasing evidence shows that phenotypic variance is genetically determined, but the underlying mechanisms of genetic control over the variance remain obscure. Here, we conducted variance-association mapping analyses to identify expression variability QTLs (evQTLs), i.e. genomic loci associated wit...
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| Publicado no: | Hum Mol Genet |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6078589/ https://ncbi.nlm.nih.gov/pubmed/28171656 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw314 |
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