Regenerating hair cells in vestibular sensory epithelia from humans

Human vestibular sensory epithelia in explant culture were incubated in gentamicin to ablate hair cells. Subsequent transduction of supporting cells with ATOH1 using an Ad-2 viral vector resulted in generation of highly significant numbers of cells expressing the hair cell marker protein myosin VIIa...

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Veröffentlicht in:eLife
Hauptverfasser: Taylor, Ruth Rebecca, Filia, Anastasia, Paredes, Ursula, Asai, Yukako, Holt, Jeffrey R, Lovett, Michael, Forge, Andrew
Format: Artigo
Sprache:Inglês
Veröffentlicht: eLife Sciences Publications, Ltd 2018
Schlagworte:
Human Biology and Medicine
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078492/
https://ncbi.nlm.nih.gov/pubmed/30019672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.34817
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