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Regenerating hair cells in vestibular sensory epithelia from humans

Human vestibular sensory epithelia in explant culture were incubated in gentamicin to ablate hair cells. Subsequent transduction of supporting cells with ATOH1 using an Ad-2 viral vector resulted in generation of highly significant numbers of cells expressing the hair cell marker protein myosin VIIa...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Taylor, Ruth Rebecca, Filia, Anastasia, Paredes, Ursula, Asai, Yukako, Holt, Jeffrey R, Lovett, Michael, Forge, Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078492/
https://ncbi.nlm.nih.gov/pubmed/30019672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.34817
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