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Structural Studies of Thiamin Monophosphate Kinase in Complex with Substrates and Products(,)

Thiamin monophosphate kinase (ThiL) catalyzes the ATP-dependent phosphorylation of thiamin monophosphate (TMP) to form thiamin pyrophosphate (TPP), the active form of vitamin B(1). ThiL is a member of a small ATP binding superfamily that also includes the purine biosynthetic enzymes, PurM and PurL,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biochemistry
Hauptverfasser: McCulloch, Kathryn M., Kinsland, Cynthia, Begley, Tadhg P., Ealick, Steven E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6078389/
https://ncbi.nlm.nih.gov/pubmed/18311927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800041h
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